{"id":10062,"date":"2023-05-18T11:23:06","date_gmt":"2023-05-18T09:23:06","guid":{"rendered":"https:\/\/wpd.ugr.es\/~aagil\/?page_id=10062"},"modified":"2025-07-25T11:25:00","modified_gmt":"2025-07-25T09:25:00","slug":"publications","status":"publish","type":"page","link":"https:\/\/wpd.ugr.es\/~aagil\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"10062\" class=\"elementor elementor-10062\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0adb477 elementor-section-full_width qode_elementor_container_inner elementor-section-stretched elementor-section-height-default elementor-section-height-default parallax_section_no\" data-id=\"0adb477\" data-element_type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;,&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ca7ab9f\" data-id=\"ca7ab9f\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3b6d894 elementor-widget elementor-widget-text-editor\" data-id=\"3b6d894\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.14.0 - 26-06-2023 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<h2><span style=\"color: #ffffff;\">Publications<\/span><\/h2>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1bdf190 elementor-section-full_width qode_elementor_container_inner elementor-section-height-default elementor-section-height-default parallax_section_no\" data-id=\"1bdf190\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2c7b354\" data-id=\"2c7b354\" data-element_type=\"column\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-2d4d124 elementor-section-full_width elementor-section-height-default elementor-section-height-default parallax_section_no qode_elementor_container_no\" data-id=\"2d4d124\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-inner-column elementor-element elementor-element-f212bca\" data-id=\"f212bca\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-dfd2af0 elementor-widget elementor-widget-text-editor\" data-id=\"dfd2af0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h6><strong>Salagre D, Sanju\u00e1n-Hidalgo J, Elmahallawy EK, Medina PP, Agil A.<\/strong><\/h6><p>MT2 receptor mediates melatonin-induced thermogenic program in human myoblasts: insights for circadian syndrome and diabesity treatment. Front Pharmacol. 2025 Jul 8;16:1633326. doi: 10.3389\/fphar.2025.1633326.<\/p><h6><strong>Salagre D, Navarro-Alarc\u00f3n M, Gonz\u00e1lez LG, Elrayess MA, Villal\u00f3n-Mir M, Haro-L\u00f3pez R, Agil A.<\/strong><\/h6><p>Melatonin Ameliorates Organellar Calcium Homeostasis, Improving Endoplasmic Reticulum Stress-Mediated Apoptosis in the Vastus Lateralis Muscle of Both Sexes of Obese Diabetic Rats.\u00a0Antioxidants\u00a02025,\u00a014, 16. https:\/\/doi.org\/10.3390\/antiox14010016<\/p><h6><strong>Salagre D, Bajit H, Fern\u00e1ndez-V\u00e1zquez G, Dwairy M, Garz\u00f3n I, Haro-L\u00f3pez R, Agil A. <\/strong><\/h6><p>Melatonin induces fiber switching by improvement of mitochondrial oxidative capacity and function via NRF2\/RCAN\/MEF2 in the vastus lateralis muscle from both sex Z\u00fccker diabetic fatty rats. Free Radic Biol Med. 2024 Dec 5;227:322-335. doi: 10.1016\/j.freeradbiomed.2024.12.019.<\/p><h6><strong>Salagre D, Navarro-Alarc\u00f3n M, Villal\u00f3n-Mir M, Alc\u00e1zar-Navarrete B, G\u00f3mez-Moreno G, Tamimi F, Agil A. <\/strong><\/h6><p>Chronic melatonin treatment improves obesity by inducing uncoupling of skeletal muscle SERCA-SLN mediated by CaMKII\/AMPK\/PGC1\u03b1 pathway and mitochondrial biogenesis in female and male Z\u00fccker diabetic fatty rats. Biomed Pharmacother. 2024 Mar;172:116314.<\/p><p>doi: 10.1016\/j.biopha.2024.116314.\u00a0 doi: 10.1016\/j.biopha.2024.116411.<\/p><h6>S\u00e1nchez-Borja C, Crist\u00f3bal-Ca\u00f1adas D, Rodr\u00edguez-Lucenilla MI, Mu\u00f1oz-Hoyos A, Agil A, V\u00e1zquez-L\u00f3pez M\u00c1, Parr\u00f3n-Carre\u00f1o T, Nievas-Soriano BJ, Bonillo-Perales A, Bonillo-Perales JC. Lower plasma melatonin levels in non-hypoxic premature newborns associated with neonatal pain. Eur J Pediatr. 2024 Aug;183(8):3607-3615.<\/h6><p>doi: 10.1007\/s00431-024-05632-1.<\/p><h6>Salagre D, Raya \u00c1lvarez E, Cendan CM, Aouichat S, Agil A<strong>.<\/strong> Melatonin Improves Skeletal Muscle Structure and Oxidative Phenotype by Regulating Mitochondrial Dynamics and Autophagy in Z\u00fccker Diabetic Fatty Rat. Antioxidants (Basel). 2023 Jul 27;12(8):1499.<\/h6><p>doi: 10.3390\/antiox12081499.<strong>\u00a0<\/strong><\/p><p><strong>\u00a0<\/strong><\/p><h6><strong>Di\u00e9guez E, Nieto-Ruiz A, Sep\u00falveda-Valbuena A, Herrmann F, Agil A , De-Castellar R, Jim\u00e9nez J, Azaryah H, Garc\u00eda-Santos JA, Garc\u00eda-Berm\u00fadez M and Campoy C.<\/strong><\/h6><p><span style=\"font-weight: 400;\">Long-term effects and potential impact of early nutrition with breast milk or infant formula on glucose homeostasis control in healthy children at 6 years old: a follow-up from the COGNIS study. Nutrients 2023, 15(4), 852; <a href=\"https:\/\/doi.org\/10.3390\/nu15040852\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.3390\/nu15040852<\/a><\/span><\/p><h6><strong>Alsharif KF, Albrakati A, Al Omairi NE, Almalki AS, Alsanie WF, Elmageed ZYA, Habotta OA, Lokman MS, Althagafi HA, Alghamdi AAA, Moneim AEA, Alyami H, Belal SKM, Alnefaie G, Alamri AS, Albezrah NKA, Kassab RB, Albarakati AJA, Hassan KE, Agil A.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Therapeutic antischizophrenic activity of prodigiosin and selenium co-supplementation against amphetamine hydrochloride-induced behavioral changes and oxidative, inflammatory, and apoptotic challenges in rats. Environ Sci Pollut Res Int. 2023.30(3):7987-8001. doi: 10.1007\/s11356-022-22409-x<\/span><\/p><h6>\u00a0<\/h6><h6><span style=\"font-weight: 400;\"><strong>Aouichat S, Raya E, Molina-Carballo A, Munoz-Hoyos A, Saleh Aloweidi A, Elmahallawy KE, Agil A (corresponding autor).<\/strong>\u00a0<\/span><\/h6><p><span style=\"font-weight: 400;\">Dose-Dependent Effect of Melatonin on BAT Thermogenesis in Z\u00fccker Diabetic Fatty Rat: Future Clinical Implications for Obesity. Antioxidants. 2022. DOI: 10.3390\/cimb44010003.<\/span><\/p><h6>\u00a0<\/h6><h6><span style=\"font-weight: 400;\"><strong>Salagre D, Chayah M, Molina-Carballo A, Oliveras-L\u00f3pez MJ, Munoz-Hoyos A, Navarro-Alarc\u00f3n M, Fern\u00e1ndez-V\u00e1zquez G, Agil A (corresponding autor).<\/strong>\u00a0<\/span><\/h6><p><span style=\"font-weight: 400;\">Melatonin induces fat browning by transdifferentiating white adipocytes and de novo differentiation of mesenchymal stem cells. Food Funct. 2022. 21;13(6):3760-3775.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Molina-Carballo A, Palacios-Lopez R, Jerez-Calero A, Augustin-Morales MC,\u00a0 Agil A,\u00a0 \u00a0 Munoz-Hoyos A, Munoz-Gallego A.<\/strong><\/h6><p><span style=\"font-weight: 400;\">Protective Effect of Melatonin Administration against SARS-CoV-2 Infection: A Systematic Review. Curr. Issues Mol. Biol. 2022. 44 (1). 31-45<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Agil A (corresponding author). Navarro-Alarcon M, Ali FAZ, Albrakati A, Salagre D, Campoy C, Elmahallawy EK.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Melatonin Enhances the Mitochondrial Functionality of Brown Adipose Tissue in Obese-Diabetic Rats. Antioxidants. 2021. 17; 10(9):1482.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Navarro-Alarc\u00f3n M, Gil-Hern\u00e1ndez F, S\u00e1nchez-Gonz\u00e1lez C, Llopis J, Villal\u00f3n-Mir M, Olmedo P, Alarc\u00f3n-Guijo P, Salagre P, Gaona L, Paredes M, Agil A (corresponding autor).\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Melatonin Improves Levels of Zn and Cu in the Muscle of Diabetic Obese Rats. Pharmaceutics. 2021. 13 (10, 1535.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><span style=\"font-weight: 400;\"><strong>Aouichat S, Chayah M, Bouguerra-Aouichat S, Agil A (corresponding autor). 2020.\u00a0<\/strong> <\/span><\/h6><p><span style=\"font-weight: 400;\">Time-restricted Feeding Improves body weight gain, lipid profile, and atherogenic Indices in Cafeteria Diet-fed Rats: Role of browning Inguinal White Adipose Tissue. Nutrients. 23; 12(8):2185.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Agil A (corresponding autor), Chayah M, Visiedo L, Navarro-Alarcon M, Reiter JR, Fern\u00e1ndez-V\u00e1zquez G. 2020.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Melatonin improves the mitochondrial dynamics and functions in the kidney of Zuker diabetic fatty rats. J Clin Med. 10; 9(9):E2916.<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Elmahallawy EK, Elshopakey GE, Saleh AA, Agil A, El-Morsey A, El-Shewehy DMM, Sad AS, Yanai T, Abdo W. 2020.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">S-Methylcysteine (SMC) Ameliorates Intestinal, Hepatic, and Splenic Damage Induced by Cryptosporidium parvum Infection via Targeting Inflammatory Modulators and OxidativeStress in Swiss Albino Mice. Biomedicines. 15; 8(10):423.<\/span><\/p><p><span style=\"font-weight: 400;\">\u00a0<\/span><\/p><h6><strong>Garc\u00eda\u2010Galdeano JM, Villal\u00f3n\u2010Mir M, Medina\u2010Mart\u00ednez J, V\u00e1zquez\u2010Foronda LM, Zamora\u2010Bustillos JG, Agil A,\u00a0 Moor\u2010Davie SM, Navarro\u2010Alarc\u00f3n M.<\/strong><\/h6><p><span style=\"font-weight: 400;\">Zn, Cu, and Fe Concentrations in Dehydrated Herbs (Thyme, Rosemary, Cloves, Oregano, and Basil) and the Correlation with the Microbial Counts of Listeria monocytogenes and Other Foodborne pathogens. Foods. 1658; doi:10.3390\/ foods9111658.<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Fernandez Vazquez G , Reiter RJ , Agil A (corresponding autor).<\/strong><\/h6><p><span style=\"font-weight: 400;\">Melatonin increases brown adipose tissue mass and functionality in Z\u00fccker diabetic fatty rats: implications for obesity control. Journal of Pineal Research. 2018 Feb 6. doi: 10.1111 \/ jpi.12472.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Alarcon-Navarro M, Villalon M, Jones C, Quesada-Granados J, Agil A (corresponding autor). 2018.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Melatonin increases magnesium concentrations in white adipose tissue and pancreas of diabetic obese rats. Journal of Functional Foods. 2018. (48)167-172.<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Campos D, Hern\u00e1ndez-Torres JJ, Agil A, Comino M, L\u00f3pez JC, Mac\u00edas V, Campoy C.<\/strong><\/h6><p><span style=\"font-weight: 400;\">Analysis of food advertising to children on Spanish television: probing exposure to television marketing. Arch Med Sci. 2016 Aug 1;12(4):799-807. doi: 10.5114\/aoms.2016.60969. Epub 2016 Jul 1.PMID: 27478462 799\u2013807. 2016.<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Masocha W, Gonzalez GL, Agil A (corresponding autor).<\/strong><\/h6><p><span style=\"font-weight: 400;\">Distinguishing subgroups among \u03bc-opioid receptor agonists using Na+,K+-ATPase as an effector mechanism. European Journal of Pharmacology. 2016 Mar 5; 774:43-9. doi: 10.1016\/j.ejphar. 2016. 01.010. Epub 2016 Jan 26.PMID: 26825542\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Elmahallawy EK, Luque JO, Aloweidi AS, Fern\u00e1ndez JG, Mart\u00ednez\u00a0 AS, Rodriguez-Granger J, Kaki A, Agil A (corresponding autor).\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Potential relevance of melatonin against some infectious agents: A Review and Assessment of Recent Research. Curr Med Chem. 2015; 22(33):3848-61.PMID: 26310920<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Berglund sk, Garc\u00eda-vald\u00e9s l, Torres-espinola fj, Segura mt, Mart\u00ednez-zald\u00edvar c, aguilar mj, Agil a, Lorente ja, Florido j, Padilla c, Altm\u00e4e s, marcos a, l\u00f3pez-sabater mc, campoy c; Preobe Team.<\/strong><\/h6><p><span style=\"font-weight: 400;\">Maternal, fetal and perinatal alterations associated with obesity, overweight and gestational diabetes: an observational cohort study (preobe). BMC public health. 2016 mar 1; 16:207. doi: 10.1186\/s12889-016-2809-3.pmid: 26931143\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Torres-Esp\u00ednola FJ, Altm\u00e4e S, Segura MT, Jerez A , Anjos Tania, Chisaguano M, L\u00f3pez-Sabater MC, Entrala C , Alvarez JC, Agil A , Florido J, Catena A, P\u00e9rez-Garc\u00eda M, Campoy M.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Maternal PPARG Pro12Ala polymorphism is associated with infant&#8217;s neurodevelopmental outcomes at 18 months of age. Early Hum Dev. 2015 Aug; 91(8):457-62. doi:10.1016\/j.earlhumdev.2015.05. 001. Epub 2015 May 26.PMID: 26025336.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Catena A, P\u00e9rez-Garc\u00eda M, Lorente JA, Alvarez JC, Agil A, Marcos A, Nova E, L\u00f3pez-Sabater MC, Entrala C, McArdle H, Symonds M, Koletzko B, Demmelmair H, Uhl O, Desoye G, Rueda R, Berglund SK).<\/strong><\/h6><p><span style=\"font-weight: 400;\">Maternal Obesity, Overweight and Gestational Diabetes Affect the Offspring Neurodevelopment at 6 and 18 Months of Age-A Follow Up from the PREOBE Cohort. PLoS One. 2015 Jul 24; 10(7): e0133010. doi: 0.1371\/journal. pone.0133010. eCollection 2015.PMID: 26208217.<\/span><\/p><h6>\u00a0<\/h6><h6><span style=\"font-weight: 400;\"><strong>Elmahallawy EK, Agil A (corresponding author).<\/strong>\u00a0<\/span><\/h6><p><span style=\"font-weight: 400;\">Treatment of Leishmaniasis: A Review and Assessment of Recent Research. Curr Pharm Des. 2015; 21(17):2259-75.PMID: 25543123.<\/span><\/p><p><span style=\"font-weight: 400;\">(I. F: 3,052, Pharmacoloy &amp; Pharmacy (9\/57; Q1; N\u00ba de citaciones 6)<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Agil A (corresponding author), Elmahallawy EK, Rodr\u00edguez-Ferrer JM, Adem A, Bastaki SM, Al-Abbadi I, Fino Solano YA, Navarro-Alarc\u00f3n M.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Melatonin increases intracellular calcium in the liver, muscle, white adipose tissues and pancreas of diabetic obese rats.\u00a0 Food Function. 2015 Aug; 6(8):2671-8. doi: 10.1039\/c5fo00590f. Epub 2015 Jul 2.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Agil A (corresponding author), El-Hammadi M, Jim\u00e9nez-Aranda A, Tassi M, Abdo W, Fern\u00e1ndez-V\u00e1zquez G, Reiter RJ.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Melatonin Reduces Hepatic Mitochondrial Dysfunction in Diabetic Obese Rats. J Pineal Res. 2015 Aug; 59(1):70-9. doi: 10.1111\/jpi.12241. Epub 2015 May 14.PMID: 25904243\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Rom\u00e1n S, Agil A (corresponding author), Per\u00e1n M, Alvaro-Galue E, Ruiz-Ojeda FG, Marchal JA.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Brown adipose tissue and novel therapeutic approaches to treat metabolic disorders.Transl Res. 2015 Apr; 165(4):464-79. doi: 10.1016\/j.trsl.2014.11.002. Epub 2014 Nov 8.PMID: 25433289<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Ojha Sh, Alkaabi J, Amir N, Sheikh A, Agil A, Abdelmonem M, Adem A.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Withania coagulans fruit extract reduces oxidative stress and inflammation in\u00a0 kidneys of streptozotocin-induced diabetic rats. Oxidative Medicine and Cellular Longevit. 2014; 201436. doi: 10.1155\/2014\/201436. Epub 2014 Sep 14.PMID: 25295146.<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Elmahallawy EK, Sampedro Martinez A, Rodriguez-Granger J, Hoyos-Mallecot Y, Agil A, Navarro Mari JM, Gutierrez Fernandez J.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Diagnosis of leishmaniasis. J Infect Dev Ctries. 2014 Aug 13; 8(8):961-72. doi: 10.3855\/jidc.4310. Review.PMID: 25116660.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Ram\u00edrez A; Boulaiz H; Morata-Tarifa C; Per\u00e1n M; Jim\u00e9nez G; Picon-Ruiz M; Agil A; Cruz-L\u00f3pez O; Conejo-Garc\u00eda A; Campos JM; S\u00e1nchez A; Garc\u00eda MA; Marchal JA.<\/strong><\/h6><p><span style=\"font-weight: 400;\">HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound. Oncotarget. 2014 Jun 15; 5(11):3590-606.PMID: 24946763.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Blanca- Herrera MR, Ruiz-Ojeda FJ, Mohamad-Akeel-Serrano M,\u00a0 Acuna Castroviejo D, Fern\u00e1ndez-V\u00e1zquez G; Agil A (corresponding autor).\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Melatonin and metabolic regulation: a review. Food Funcion., 5 (2806-2832), 2806. 2014. Review<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Elmahallawy E, Jim\u00e9nez-Aranda A, Sampedro Mart\u00ednez A, Rodriguez-Granger J, Navarro-Alarc\u00f3n M; Guti\u00e9rrez Fern\u00e1ndez J, Agil A (corresponding author).\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Activity of melatonin against Leishmaniainfantum promastigotes by mitochondrial dependent pathway. Chemico-Biological Interactions. Chemico-Biological Interactions. 2014 Sep 5;220:84-93. doi: 10.1016\/j.cbi.2014.06.016. Epub 2014 Jun.25. PMID: 24973643\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Reina de la Torre ML, Navarro-Alarc\u00f3n M, del Moral LM, L\u00f3pez-G de la Serrana H, Palomares-Bayo M, Oliveras L\u00f3pez MJ, Blanca Herrera RM, Agil A (corresponding autor). <\/strong><\/h6><p><span style=\"font-weight: 400;\">Serum Zn levels and Cu\/Zn ratios worsen in hemodialysis patients, implying increased cardiovascular risk: a 2-year longitudinal study. Biol Trace Elem Res. 2014 May;158(2):129-35. doi: 10.1007\/s12011-014-9921-y. Epub 2014 Mar 2. PMID: 24585396.<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Jimen\u00e9z-Aranda A, Fern\u00e1ndez-V\u00e1zquez G, Serrano MM, Reiter RJ, Agil A (corresponding autor).<\/strong><\/h6><p><span style=\"font-weight: 400;\">Melatonin improves mitochondrial function in inguinal white adipose tissue of Z\u00fccker diabetic fatty rats. J Pineal Res. 2014 Aug;57(1):103-9. doi: 10.1111\/jpi.12147. Epub 2014 Jul 10.PMID: 24867433\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Navarro-Alarcon M, Ruiz-Ojeda FJ, Blanca-Herrera RM, Kaki A, Adem A, Agil A (corresponding autor).<\/strong><\/h6><p><span style=\"font-weight: 400;\">Melatonin administration in diabetes: regulation of plasma Cr, V, and Mg in young male Zucker diabetic fatty rats. Food Funct. 2014 Mar; 5(3):512-6. doi: 10.1039\/c3fo60389j. PMID: 24441643.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Jim\u00e9nez-Aranda A, Fern\u00e1ndez-V\u00e1zquez G, Campos D, Tassi M, Velasco-Perez L, Tan DX, Reiter RJ, Agil A (corresponding autor).\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Melatonin induces browning of inguinal white adipose tissue in Zucker diabetic fatty rats. J Pineal Res. 2013 Nov;55(4):416-23. doi: 10.1111\/jpi.12089. Epub 2013 Sep 6. PMID: 24007241.<\/span><\/p><h6>\u00a0<\/h6><h6><span style=\"font-weight: 400;\"><strong>Agil A (corresponding autor), Reiter RJ, Jim\u00e9nez-Aranda A, Ib\u00e1n-Arias R, Navarro-Alarc\u00f3n M, Marchal JA, Adem A, Fern\u00e1ndez-V\u00e1zquez G.<\/strong>\u00a0<\/span><\/h6><p><span style=\"font-weight: 400;\">Melatonin ameliorates low-grade inflammation and oxidative stress in young Zucker diabetic fatty rats. J Pineal Res. 2013 May;54(4):381-8. doi: 10.1111\/jpi.12012. Epub 2012 Sep 29. PMID: 23020082\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Marchal JA, Carrasco E, Ramirez A, Jim\u00e9nez G, Olmedo C, Peran M, Agil A, Conejo-Garc\u00eda A, Cruz-L\u00f3pez O, Campos JM, Garc\u00eda M\u00c1.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFN\u03b1 triggering apoptosis, autophagy and senescence. Drug Des Devel Ther. 2013 Oct 29; 7:1301-13. doi: 10.2147\/DDDT.S51354. eCollection 2013. PMID: 24194639 PMCID: PMC3815003.<\/span><\/p><h6>\u00a0<\/h6><h6><span style=\"font-weight: 400;\"><strong>Navarro-Alarcon M, Ruiz-Ojeda FJ, Blanca-Herrera RM, Agil A (corresponding autor).<\/strong> <\/span><\/h6><p><span style=\"font-weight: 400;\">Antioxidant activity of melatonin in diabetes in relation to the regulation and levels of plasma Cu, Zn, Fe, Mn, and Se in Zucker diabetic fatty rats. Nutrition. 2013 May; 29(5):785-9. doi: 10.1016\/j.nut.2012.11.005. Epub 2013 Jan 24. PMID: 23352467\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Ram\u00edrez-Mac\u00edas I, Mar\u00edn C, Samti H, Fern\u00e1ndez A, Guardia JJ, Zentar H, Agil A, Chahboun R, Alvarez-Manzaneda E, S\u00e1nchez-Moreno M.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Taiwaniaquinoid and abietane quinone derivatives with trypanocidal activity against T. cruzi and Leishmania spp. Parasitol Int. 2012 Sep;61(3):405-13. doi: 10.1016\/j.parint. 2012. 02.001. Epub 2012 Feb 16. PMID: 22366342.<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Agil A (corresponding autor), Rosado <\/strong><strong>I, Ruiz R, Figueroa A, Zen N, Fern\u00e1ndez-V\u00e1zquez G. <\/strong><\/h6><p><span style=\"font-weight: 400;\">Melatonin improves glucose homeostasis in young Zucker diabetic fatty rats. J Pineal Res. 2012 Mar;52(2):203-10. doi: 10.1111\/j.1600-079X.2011.00928.x. Epub 2011 Aug 25. PMID: 21883445.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Gonzalez LG, Masocha W, S\u00e1nchez-Fern\u00e1ndez C, Agil A (corresponding autor), Oca\u00f1a M, Del Pozo E, Baeyens JM.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Changes in morphine-induced activation of cerebral Na(+),K(+)-ATPase during morphine tolerance: biochemical and behavioral consequences. Biochem Pharmacol. 2012 Jun 1; 83(11):1572-81. doi: 10.1016\/j.bcp.2012.02.023. Epub 2012 Mar 3. PMID: 22410004.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Navarro-Alarcon M, Zambrano E, Moreno-Montoro M, Agil A, Olalla M.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Duplicate portion sampling combined with spectrophotometric analysis affords the most accurate results when assessing daily dietary phosphorus intake. Nutr Res. 2012 Aug;32(8):573-80. doi: 10.1016\/j.nutres.2012.06.013. Epub 2012 Jul 31. PMID: 22935340\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Agil A(corresponding autor), Navarro-Alarc\u00f3n M, Ruiz R, Abuhamadah S, El-Mir MY, V\u00e1zquez GF.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Beneficial effects of melatonin on obesity and lipid profile in young Zucker diabetic fatty rats. J Pineal Res. 2011 Mar;50(2):207-12. doi: 10.1111\/j.1600-079X.2010.00830.x. Epub 2010 Nov 19. PMID: 21087312.<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Mart\u00ed del Moral L, Agil A, Navarro-Alarc\u00f3n M, L\u00f3pez-Ga de la Serrana H, Palomares-Bayo M, Oliveras-L\u00f3pez MJ.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Altered serum selenium and uric acid levels and dyslipidemia in hemodialysis patients could be associated with enhanced cardiovascular risk. Biol Trace Elem Res. 2011 Dec;144(1-3):496-503. doi: 10.1007\/s12011-011-9152-4. Epub 2011 Jul 26. PMID: 2178954.<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Mart\u00ednez-Peinado M, Nogueras-L\u00f3pez F, Arcos-Cebri\u00e1n A, Agil A, Navarro-Alarc\u00f3n M. <\/strong><\/h6><p><span style=\"font-weight: 400;\">Serum selenium levels in cirrhotic patients are not influenced by the disease severity index. Nutr Res. 2010 Aug;30(8):574-8. doi: 10.1016\/j.nutres.2010.08.004. PMID: 20851312.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Velasco-Reynold C, Navarro-Alarcon M, Lopez-Ga de la Serrana H, Perez-Valero V, Agil A, Lopez-Martinez MC. <\/strong><\/h6><p><span style=\"font-weight: 400;\">Dialysability of magnesium and calcium from hospital duplicate meals: influence exerted by other elements. Biol Trace Elem Res. 2010 Mar;133(3):313-24. doi: 10.1007\/s12011-009-8444-4. Epub 2009 Jul 7. PMID: 19582377.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>CampoyC , E. Mart\u00edn-Bautista, L. Garc\u00eda-Vald\u00e9s, J. Florido, A. Agil, J. A. Lorente, A. Marcos, M. C. L\u00f3pez-Sabater, T. Miranda-Le\u00f3n, Y. Sanz y J. A. Molina-Font.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Estudio de la influencia de la nutrici\u00f3n y gen\u00e9tica maternas sobre la programaci\u00f3n del desarrollo del tejido adiposo fetal (Estudio PREOBE). Nutr Hosp. 2008 Nov-Dec; 23(6):584-90.PMID: 19132267<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Agil A (corresponding author), Dur\u00e1n R, Barrero F, Morales B, Ara\u00fazo M, Alba F, Miranda MT, Prieto I, Ram\u00edrez M, Vives F.<\/strong><\/h6><p><span style=\"font-weight: 400;\">Plasma lipid peroxidation in sporadic Parkinson&#8217;s disease. Role of the L-dopa. J Neurol Sci. 2006 Jan 15;240(1-2):31-6. Epub 2005 Oct 10. PMID: 16219327 DOI: 10.1016\/j.jns.2005.08.016\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Ruiz JR, Ortega FB, Castillo MJ, Gutierrez A, Agil A (corresponding author).\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Increased susceptibility to plasma lipid peroxidation in untrained subjects after an extreme mountain bike challenge at moderate altitude. Int J Sports Med. 2006 Jul;27(7):587-9. PMID: 16802256.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Mart\u00ednez-Ballesteros C, Pita-Calandre E, S\u00e1nchez-Gonz\u00e1lez Y, Rodr\u00edguez-L\u00f3pez CM, Agil A (corresponding autor).\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Lipid peroxidation in adult epileptic patients treated with valproic acid. Rev Neurol. 2004 Jan 16-31;38(2):101-6. PMID: 14752705.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Masocha W, Horvath G, Agil A, Ocana M, Del Pozo E, Szikszay M, Baeyens JM.<\/strong><\/h6><p><span style=\"font-weight: 400;\">Role of Na(+), K(+)-ATPase in morphine-induced antinociception. J Pharmacol Exp Ther. 2003 Sep; 306(3):1122-8. Epub 2003 May 19. PMID: 12756273.<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Horvath G, Agil A, Joo G, Dobos I, Benedek G, Baeyens JM.<\/strong><\/h6><p><span style=\"font-weight: 400;\">\u00a0Evaluation of endomorphin-1 on the activity of Na(+),K(+)-ATPase using in vitro and in vivo studies. Eur J Pharmacol. 2003 Jan 5; 458(3):291-7. PMID: 12504785.<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Montilla MP, Agil A, Navarro MC, Jim\u00e9nez MI, Garc\u00eda-Granados A, Parra A, Cabo MM.<\/strong><\/h6><p><span style=\"font-weight: 400;\"> Antioxidant activity of maslinic acid, a triterpene derivative obtained from Olea europaea. Planta Med. 2003 May; 69(5):472-4. PMID: 12802735 DOI: 10.1055\/s-2003-39698.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Masocha W, Gonz\u00e1lez LG, Baeyens JM, Agil A (corresponding author).\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Mechanisms involved in morphine-induced activation of synaptosomal Na+,K+-ATPase. Brain Res.\u00a0 2002 Dec 3; 957(2): 311-9. PMID: 12445973.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Agil A, Sadrzadeh SM.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Hydroxy-urea protects erythrocytes against oxidative damage. Redox Rep. 2000; 5(1):29-34. PMID: 10905541 DOI: 10.1179\/rer.2000.5.1.29.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Agil A, Mir\u00f3 M, Jimenez J, Aneiros J, Caracuel MD, Garc\u00eda-Granados A, Navarro MC. <\/strong><\/h6><p><span style=\"font-weight: 400;\">Isolation of ani-hepatotoxic principle form the juice of Ecballium elaterium. Planta Med. 1999 Oct; 65(7):673-5. PMID: 15609462. DOI: 10.1055\/s-2006-960847.<\/span><\/p><h6>\u00a0<\/h6><h6><span style=\"font-weight: 400;\"><strong>Agil A, R\u00edsco S, Mir\u00f3 M, Navarro MC, Ocete MA, y Jimenez J.<\/strong>\u00a0<\/span><\/h6><p><span style=\"font-weight: 400;\">Analgesic and antipyretic effects of Ecballium elaterium (l) A.R. in rodents. Phytotherapy research 9, 135-138. 1995.\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Ginsburg GS, Agil A, O&#8217;Toole M, Rimm E, Douglas PS, Rifai N.<\/strong><\/h6><p><span style=\"font-weight: 400;\">Effects of a single bout of ultra-endurance exercise on lipid levels and susceptibility of lipids to peroxidation in triathletes.JAMA. 1996 Jul 17; 276(3):221-5.PMID: 8667567<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Haffner SM, Miettinen H, Stern MP, Agil A, Jialal I.\u00a0<\/strong><\/h6><p><span style=\"font-weight: 400;\">Plasma oxidizability in Mexican-Americans and non-Hispanic whites. Metabolism. 1996 Jul; 45(7):876-81.PMID: 8692025\u00a0<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Haffner SM, Agil A, Mykkanen L, Stern MP, Jialal I. <\/strong><\/h6><p><span style=\"font-weight: 400;\">Plasma oxidizability in subjects with normal glucose tolerance, impaired glucose tolerance, and NIDDM. Diabetes Care. 1995 May;18(5):646-53. PMID: 8586002<\/span><\/p><h6>\u00a0<\/h6><h6><strong>Agil A, Fuller CJ, Jialal I.<\/strong><\/h6><p><span style=\"font-weight: 400;\">Susceptibility of plasma to ferrous iron\/hydrogen peroxide-mediated oxidation: demonstration of a possible Fenton reaction. Clin Chem. 1995 Feb;41(2):220-5.PMID: 7874775.\u00a0<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Publications Salagre D, Sanju\u00e1n-Hidalgo J, Elmahallawy EK, Medina PP, Agil A. MT2 receptor mediates melatonin-induced thermogenic program in human myoblasts: insights for circadian syndrome and diabesity treatment. Front Pharmacol. 2025 Jul 8;16:1633326. doi: 10.3389\/fphar.2025.1633326. Salagre D, Navarro-Alarc\u00f3n M, Gonz\u00e1lez LG, Elrayess MA, Villal\u00f3n-Mir M, Haro-L\u00f3pez&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"full_width.php","meta":[],"_links":{"self":[{"href":"https:\/\/wpd.ugr.es\/~aagil\/wp-json\/wp\/v2\/pages\/10062"}],"collection":[{"href":"https:\/\/wpd.ugr.es\/~aagil\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/wpd.ugr.es\/~aagil\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/wpd.ugr.es\/~aagil\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/wpd.ugr.es\/~aagil\/wp-json\/wp\/v2\/comments?post=10062"}],"version-history":[{"count":34,"href":"https:\/\/wpd.ugr.es\/~aagil\/wp-json\/wp\/v2\/pages\/10062\/revisions"}],"predecessor-version":[{"id":10738,"href":"https:\/\/wpd.ugr.es\/~aagil\/wp-json\/wp\/v2\/pages\/10062\/revisions\/10738"}],"wp:attachment":[{"href":"https:\/\/wpd.ugr.es\/~aagil\/wp-json\/wp\/v2\/media?parent=10062"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}