{"id":241,"date":"2017-02-28T11:57:26","date_gmt":"2017-02-28T10:57:26","guid":{"rendered":"http:\/\/wpd.ugr.es\/~fqm302\/blog\/?p=241"},"modified":"2018-08-26T12:12:34","modified_gmt":"2018-08-26T11:12:34","slug":"high-throughput-methodology-for-the-determination-of-carbamates-in-food-supplements-by-uhplc-msms","status":"publish","type":"post","link":"https:\/\/wpd.ugr.es\/~fqm302\/blog\/?p=241","title":{"rendered":"High-throughput methodology for the determination of carbamates in food supplements by UHPLC\u2013MS\/MS."},"content":{"rendered":"<p>Food supplements are increasingly consumed products that claim to have several benefits for health. In many cases, these supplements contain herbal products and, as a consequence, can be contaminated with pesticides used in crops. This study aimed to use a QuEChERS-based method and ultra-high performance liquid chromatography\u2013tandem mass spectrometry (UHPLC\u2013MS\/MS) to determine carbamate residues in different food supplements, all of them containing different herbal products, such as <em class=\"EmphasisTypeItalic \">Garcinia cambogia<\/em>, <em class=\"EmphasisTypeItalic \">Cynaras colymus<\/em>, <em class=\"EmphasisTypeItalic \">Equisetum arvense<\/em>, soy lecithin, <em class=\"EmphasisTypeItalic \">Spirulina maxima<\/em>, <em class=\"EmphasisTypeItalic \">Fucus vesiculosus<\/em>, olive leaf and garlic extract. After testing different sorbents, the combination of PSA\/C<sub>18<\/sub> (75\/25) provided the best clean-up effect. The method was validated in terms of linearity, matrix effect, limit of quantification, precision (intra and interday) and trueness. Good linearity (<em class=\"EmphasisTypeItalic \">r<\/em><sup>2<\/sup>\u00a0&gt;\u00a00.99) and precision lower than 16% (expressed as relative standard deviation) were obtained in all cases. Moreover, the recovery in all studied samples was within the acceptable range (71\u2013104%), and limit of quantification was 0.8\u00a0\u00b5g\u00a0kg<sup>\u22121<\/sup>. The method was proved to be successful as a quantitative method for carbamate residue analysis in various food supplements, which are known to be complex matrices.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-242\" src=\"..\/blog\/wp-content\/uploads\/2017\/02\/17Chroma80.gif\" alt=\"\" width=\"754\" height=\"476\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Food supplements are increasingly consumed products that claim to have several benefits for health. In many cases, these supplements contain herbal products and, as a consequence, can be contaminated with pesticides used in crops. This study aimed to use a &hellip; <a href=\"https:\/\/wpd.ugr.es\/~fqm302\/blog\/?p=241\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[67,74,26,86,119,57],"tags":[97,101,103],"class_list":["post-241","post","type-post","status-publish","format-standard","hentry","category-agl2015-70708-r","category-carbamates","category-mass-spectrometry","category-quechers","category-supplements","category-uhplc","tag-hplc","tag-ms","tag-quechers"],"_links":{"self":[{"href":"https:\/\/wpd.ugr.es\/~fqm302\/blog\/index.php?rest_route=\/wp\/v2\/posts\/241","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wpd.ugr.es\/~fqm302\/blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/wpd.ugr.es\/~fqm302\/blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/wpd.ugr.es\/~fqm302\/blog\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/wpd.ugr.es\/~fqm302\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=241"}],"version-history":[{"count":2,"href":"https:\/\/wpd.ugr.es\/~fqm302\/blog\/index.php?rest_route=\/wp\/v2\/posts\/241\/revisions"}],"predecessor-version":[{"id":357,"href":"https:\/\/wpd.ugr.es\/~fqm302\/blog\/index.php?rest_route=\/wp\/v2\/posts\/241\/revisions\/357"}],"wp:attachment":[{"href":"https:\/\/wpd.ugr.es\/~fqm302\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=241"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wpd.ugr.es\/~fqm302\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=241"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/wpd.ugr.es\/~fqm302\/blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=241"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}