{"id":502,"date":"2023-04-21T10:07:58","date_gmt":"2023-04-21T08:07:58","guid":{"rendered":"https:\/\/inspiringaudiologyugr.wordpress.com\/?page_id=502"},"modified":"2026-04-09T07:44:54","modified_gmt":"2026-04-09T07:44:54","slug":"e-hhl-d","status":"publish","type":"page","link":"https:\/\/wpd.ugr.es\/~sig.proc.audiology\/e-hhl-d\/","title":{"rendered":"E-HHL-D"},"content":{"rendered":"\n
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Title<\/strong>: Early detection of hearing loss through auditory evoked potentials (towards hidden hearing loss detection)<\/em> <<Detecci\u00f3n temprana de p\u00e9rdidas auditivas mediante potenciales evocados (hacia la detecci\u00f3n de la sordera oculta)>>
Acronym<\/strong>: E-HHL-D (Early Hidden Hearing Loss Detection)
Reference<\/strong>: P21_00152 (ProyExcel_00152)
Funding source<\/strong>: Proyectos de Excelencia, en el \u00e1mbito del Plan Andaluz de Investigaci\u00f3n, Desarrollo e Innovaci\u00f3n (PAIDI 2020), Convocatoria 2021. Consejer\u00eda de Universidad, Investigaci\u00f3n e Innovaci\u00f3n, Junta de Andaluc\u00eda
Duration<\/strong>: Dec 2, 2022 \u2013 Dec 31, 2025
Amount funded<\/strong>: 78.545,00 \u20ac
Participants<\/strong>: University of Granada
IP<\/strong>: \u00c1ngel de la Torre, Jos\u00e9 Carlos Segura (left on Sep 10, 2023)
Investigators<\/strong>: \u00c1ngel de la Torre, Isaac M. \u00c1lvarez, Jos\u00e9 L. Vargas, Jos\u00e9 C. Segura (left on Sep 10, 2023)
Collaborators<\/strong>: Jos\u00e9 M. Ruiz, Joaqu\u00edn T. Valderrama (joined on Dec 2, 2022; and left on Dec 31, 2023), David McAlpine (joined on Dec 2, 2022; and left on Dec 31, 2023), Jessica Monaghan (joined on Dec 2, 2022; and left on Dec 31, 2023), Juan Mart\u00edn-Lagos, Marta Mart\u00ednez, Nicol\u00e1s M\u00fcller, Dolores Alonso and Francisco A. Chiquero (joined on Jan 1, 2024)<\/p>\n<\/div>\n<\/div>\n\n\n\n

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This project will develop novel diagnostic protocols<\/strong> based on auditory evoked potentials for the early detection of hearing losses that compromise intelligibility in noisy venues without significantly affecting hearing thresholds (early stages of progressive hearing loss, presbycusis, accumulated acoustic trauma, etc.). These protocols will provide an objective evaluation of hearing loss specifically oriented towards its impact on quality of life, and particularly, on speech intelligibility and sounds segregation in noisy conditions.

Based on techniques previously developed by the research team, which facilitate the comprehensive recording of auditory evoked responses from the entire auditory pathway using complex stimuli (e.g., randomized stimuli, natural speech, or binaural stimuli), the experimental design aims to provide sensitive biomarkers to three specific neurophysiological pathologies associated with the loss of intelligibility. The comparative evaluation in groups of subjects, analyzing both subjective indicators (e.g., intelligibility in psychoacoustic speech-in-noise tests) and objective indicators based on auditory evoked potentials, will allow the development of advanced protocols for the early detection of pathologies related to hearing-in-noise difficulties, which cannot be detected by current best-practice clinical protocols (mostly focused on hearing thresholds).

The expected results<\/strong> over the 3-year duration of the project include: (A) Development of protocols for the evaluation of auditory intelligibility and associated pathologies. (B) Application of the protocols to a group of individuals with normal audiometric thresholds, with and without speech-in-noise intelligibility difficulties. (C) Identification of objective indicators oriented towards the early detection of hearing loss. (D) Development of materials and activities oriented towards scientific dissemination (encouraging the use of developed tools and technology transfer) and outreach (raising social awareness regarding auditory well-being and the prevention of auditory pathologies).<\/p>\n\n\n\n

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Journal articles<\/strong><\/p>\n\n\n\n

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A phase-demodulation based time drift compensation for the reduction of the 50\/60 Hz power line interference in biopotentials<\/strong>
de la Torre A, Alvarez IM, Mu\u00f1oz-Orellana, JA.
Biomedical Signal Processing & Control (2026<\/strong>) 115. 109423. Open access<\/strong>
[DOI]<\/a> [PDF]<\/a> [Supplementary Material (includes Matlab\/Octave code)]<\/a><\/p>\n\n\n\n

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Multi-response deconvolution of auditory evoked potentials in a reduced representation space<\/strong>
de la Torre A, Sanchez I, Alvarez IM, Segura JC, Valderrama JT, Muller N, Vargas JL.
Journal of the Acoustical Society of America (2024<\/strong>) 155, 3639\u20133653. Open access<\/strong>
[DOI]<\/a> [PDF]<\/a> [Supplementary Material (includes Matlab\/Octave code)]<\/a><\/p>\n\n\n\n

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Patents<\/strong> <\/p>\n\n\n\n