A list of a few, old relevant papers
This is just a list of a few, relevant papers. For a full list of publications, please, check my profiles at:
2013
- Fluorescence Lifetime Imaging Microscopy for the Detection of Intracellular pH with Quantum Dot Nanosensors. A. Orte, J.M. Alvarez-Pez,M.J. Ruedas-Rama. ACS Nano (2013), 7, 6387.
- Real-Time Phosphate Sensing in Living Cells using Fluorescence Lifetime Imaging Microscopy (FLIM). J.M. Paredes, M.D. Giron, M.J. Ruedas-Rama, A. Orte, L. Crovetto, E.M. Talavera, R. Salto, J.M. Alvarez-Pez. J. Phys. Chem. B (2013), 117, 8143.
2012
- A chloride ion nanosensor for time-resolved fluorimetry and fluorescence lifetime imaging. M.J. Ruedas-Rama, A. Orte, E.A.H. Hall, J.M. Alvarez-Pez, E.M. Talavera. Analyst (2012), 137, 1500-1508.
- Fluorescent nanoparticles for intracellular sensing: A review. M.J. Ruedas-Rama, J.D. Walters, A. Orte, E.A.H. Hall. Anal. Chim. Acta(2012), 751, 1-23. A review.
- Direct Observation of the Interconversion of Normal and Toxic Forms of alpha-Synuclein. N. Cremades, S.I.A. Cohen, E. Deas, A.Y. Abramov, A.Y. Chen, A.Orte, M. Sandal, R.W. Clarke, P. Dunne, F.A. Aprile, C.W. Bertoncini, N.W. Wood, T.P.J. Knowles, C.M. Dobson, D. Klenerman. Cell (2012), 149, 1048-1059.
- Early Amyloidogenic Oligomerization Studied through Fluorescence Lifetime Correlation Spectroscopy. J.M. Paredes, S. Casares, M.J. Ruedas-Rama, E. Fernandez, F. Castello, L. Varela, A. Orte. Int. J. Mol. Sci. (2012), 13, 9400-9418.
- Bulk and Single-Molecule Fluorescence Studies of the Saturation of the DNA Double Helix Using YOYO-3 Intercalator Dye. S.G. Lopez, M.J. Ruedas-Rama, S. Casares, J.M. Alvarez-Pez, A. Orte*. J. Phys. Chem. B (2012), 116, 11561.
- Ubiquitin chain conformation regulates recognition and activity of interacting proteins. Y. Ye, G. Blaser, M.H. Horrocks, M.J. Ruedas-Rama, S. Ibrahim, A.A. Zhukov, A. Orte, D. Klenerman, S.E. Jackson, D. Komander. Nature (2012), 492, 266.
- The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β1−40 peptide. P. Narayan, A. Orte, R.W Clarke, B. Bolognesi, S. Hook, K.A. Ganzinger, S. Meehan, M.R. Wilson, C.M. Dobson, D. Klenerman. Nature Struct. Mol. Biol. (2012), 19, 79.
2011
- Quantum dot photoluminescence lifetime-based pH nanosensor. M.J. Ruedas-Rama, A. Orte, E.A.H. Hall, J.M. Alvarez-Pez, E.M. Talavera. Chem. Commun. (2011), 47, 2898-2900.
- Influence of the solvent on the ground- and excited-state buffer-mediated proton-transfer reactions of a xanthenic dye. J.M. Paredes, L. Crovetto, A. Orte, J.M. Alvarez-Pez, E.M. Talavera. Phys. Chem. Chem. Phys. (2011), 13, 1685-1694.
- Dynamics of Water-in-Oil Nanoemulsions Revealed by Fluorescence Lifetime Correlation Spectroscopy. A. Orte, M.J. Ruedas-Rama, J.M. Paredes, L. Crovetto, J.M. Alvarez-Pez. Langmuir (2011), 27, 12792-12799.
- Single-Molecule Fluorescence Coincidence Spectroscopy and its Application to Resonance Energy Transfer. A. Orte,* R. W. Clarke, D. Klenerman. ChemPhysChem (2011), 12, 491-499. A review.
2010
- Formation of Stable BOBO-3 H-Aggregate Complexes Hinders DNA Hybridization. M.J. Ruedas-Rama, J.M. Alvarez-Pez, A. Orte*. J. Phys. Chem. B. (2010), 114, 9063-9071.
- Similarity between the kinetic paramters of the buffer-mediated proton exchange reaction of a xanthenic derivative in its ground- and excited-state. J.M. Paredes, A. Orte, L. Crovetto, J.M. Alvarez-Pez, R. Rios, M.J. Ruedas-Rama, E.M. Talavera. Phys. Chem. Chem. Phys. (2010), 12, 323-327.
- RNA Conformation in Catalytically Active Human Telomerase. J.A. Yeoman, A. Orte, B. Ashbridge, D. Klenerman, S. Balasubramanian. J. Am. Chem. Soc. (2010), 132, 2852-2853.
2009
- Single-Molecule Analysis of the Human Telomerase RNA·Dyskerin Interaction and the Effect of Dyskeratosis Congenita Mutations. B. Ashbridge, A. Orte, J.A. Yeoman, M. Kirwan, T. Vulliamy, I. Dokal, D. Klenerman, S. Balasubramanian. Biochemistry. (2009), 48, 10858-10865.
- Probing Neuroserpin Polymerization and Interaction with Amyloid-beta Peptides Using Single-Molecule Fluorescence. A. Chiou, P. Hagglof, A. Orte, A.Y. Chen, P.D. Dunne, D. Belorgey, S. Karlsson-Li, D.A. Lomas, D. Klenerman. Biophys. J. (2009), 97, 10858-10865.
2008
- Evidence of an Intermediate and Parallel Pathways in Protein Unfolding from Single-Molecule Fluroescence. A. Orte, T.D. Craggs, S.S. White, S.E. Jackson, D. Klenerman. J. Am. Chem. Soc. (2008), 130, 7898-7907.
- Direct characterization of amyloidogenic oligomers by single-molecule fluroescence. A. Orte, N.R. Birkett, R.W. Clarke, G.L. Devlin, C.M. Dobson, D. Klenerman. Proc. Natl. Acad. Sci. U.S.A. (2008), 105, 14424-14429.
- Single-molecule analysis of human telomerase monomer. D. Alves, H. Li, R. Codrington, A. Orte, X. Ren, D. Klenerman, S. Balasubramanian. Nat. Chem. Biol. (2008), 4, 287-289.
Dr A. Orte's research, teaching, and interests