PEAT-RSA-System

Title: Design, implementation and evaluation of an advanced system for recording auditory brainstem responses (ABR) based on coded signalling <<Diseño, implementación y evaluación de un sistema avanzado de registro de potenciales evocados auditivos del tronco (PEAT) basado en señalización codificada>>
Acronym: PEAT-RSA-System
Reference: TEC2009-14245
Funding source: Ministry of Science and Innovation, Government of Spain
Duration: 01/01/2010 – 31/12/2013
Amount funded: 33.500,00 €
Participants: University of Granada
IP: José C. Segura
Investigators: José C. Segura, Ángel de la Torre, Antonio Rubio, Manuel Sáinz, Carmen Benítez, Luz García, Sonia Mota, Isaac M. Álvarez, Matilde Sánchez, José L. Vargas, Joaquín T. Valderrama
Collaborators: Prof. Roger A. Thornton (MRC Institute of Hearing Research, Southampton, United Kingdom)


This project developed, implemented and validated the hardware and software of a flexible system for recording auditory brainstem responses, and formulated novel mathematical algorithms for deconvolution of overlapping auditory evoked potentials, noise reduction, and automatic quality assessment.


Journal articles

  • Valderrama J, de la Torre A, Medina C, Segura JC, Thornton ARD. Selective processing of auditory evoked responses with iterative-randomized stimulation and averaging: A strategy for evaluating the time-invariant assumption. Hearing Research (2016) 333, 66-76. doi: 10.1016/j.heares.2015.12.009. [Download]
  • Valderrama J, de la Torre A, Alvarez IM, Segura JC, Thornton ARD, Sainz M, Vargas JL. Auditory brainstem and middle latency responses recorded at fast rates with randomized stimulation. Journal of the Acoustical Society of America (2014) 136, 3233-3248. doi: 10.1121/1.4900832. [Download]
  • Valderrama J, de la Torre A, Alvarez IM, Segura JC, Sainz M, Vargas JL. A flexible and inexpensive high-performance auditory evoked response recording system appropriate for research purposes. Biomedical Engineering/Biomedizinische Technik (2014) 59, 447-459. doi: 10.1515/bmt-2014-0034. [Download]
  • Valderrama J, de la Torre A, Alvarez IM, Segura JC, Thornton ARD, Sainz M, Vargas JL. Automatic quality assessment and peak identification of auditory brainstem responses with fitted parametric peaks. Computer Methods and Programs in Biomedicine (2014) 114, 262-275. doi: 10.1016/j.cmpb.2014.02.015. [Download]
  • Valderrama J, de la Torre A, Alvarez IM, Segura JC, Thornton ARD, Sainz M, Vargas JL. A study of adaptation mechanisms based on ABR recorded at high stimulation rate. Clinical Neurophysiology (2014) 125, 805-813. doi: 10.1016/j.clinph.2013.06.190. [Download]
  • Vargas JL, Sainz M, Roldan C, Alvarez IM, de la Torre A. Analysis of electrica thresholds and maximum comfortable levels in cochlear implant patients. Auris Nasus Larynx (2013) 40, 260-265. doi: 10.1016/j.anl.2012.09.002. [Download]
  • Vargas JL, Sainz M ,Roldan C, Alvarez IM, de la Torre A. Long-term evolution of the electrical stimulation levels for cochlear implant patients. Clinical and Experimental Otorhinolaryngology (2012) 5, 194-200. doi: 10.3342/ceo.2012.5.4.194. [Download]
  • Valderrama J, de la Torre A, Alvarez IM, Segura JC, Sainz M, Vargas JL. Recording of auditory brainstem respones at high stimulation rates using randomized stimulation and averaging. Journal of the Acoustical Society of America (2012) 132, 3856-3865. doi: 10.1121/1.4764511. [Download]
  • Valderrama J, Alvarez I, de la Torre A, Segura JC, Sainz M, Vargas JL. Educational approach of a BAER recording system based on experiential learning. Technics Technologies Education Management (2011) 6, 876-889. [URL, Download]
  • Alvarez IM, de la Torre A, Valderrama J, Roldan C, Sainz M, Segura JC, Vargas JL. Changes over time of the refractory properties measured from ECAP in Pulsa CI100 cochlear implant recipients. The Journal of International Advanced Otology (2011) 7, 398-407. [URL, Download]


Students supervision

  • PhD candidate: Joaquín Tomás Valderrama Valenzuela
    Title: Development and implementation of an advanced auditory evoked response recording system. New strategies for high-rate stimulation <<Desarrollo e implementación de un sistema avanzado de registro de potenciales evocados auditivos. Nuevas estrategias de registro a alta tasa>>
    Supervisors: Ángel de la Torre, José Carlos Segura
    Department: Signal Theory, Telematics and Communications, University of Granada
    Date of the Award: 31/10/2014
    Grade: Cum Laude
    Sponsorship: [Sponsor 1] TEC2009-14245, R&D National Plan 2008-2011, Ministry of Economy and Competitivity, Government of Spain & European Regional Development Fund Programme 2007-2013. [Sponsor 2] Programa de Formación de Profesorado Universitario (FPU) AP2009-3150, Ministry of Education, Culture, and Sports, Government of Spain
    PhD thesis: Download


Conference contributions

  • de la Torre A, Valderrama J. La investigación multidisciplinar en Audiología: Estudio de los mecanismos rápidos y lentos de adaptación de los potenciales evocados auditivos. Podium presentation at the XIII Congreso Nacional de la Asociación Española de Audiología, Cartagena, Spain (May 20-21, 2016). [Program, Presentation]
  • Valderrama J, Franco M, Alvarez IM, de la Torre A, Segura JC, Sainz M, Vargas JL. Registro de potenciales evocados auditivos mediante una arquitectura modular apropiada para propósitos de investigación. Podium presentation at the 6º Simposio CEA Bioingeniería – Interfaces Mente-Computador y Neurotecnologías, Granada, Spain (June 12-13, 2014). Cognitive Area Networks ISSN: 2341-4243 1, 66-73. [Conference paper, Presentation]
  • Morales JM, Valderrama J, Alvarez IM, de la Torre A, Segura JC, Sainz M, Vargas JL. Método automático de seguimiento de respuestas evocadas auditivas basado en la parametrización de series de registros. Podium presentation at the 6º Simposio CEA Bioingeniería – Interfaces Mente-Computador y Neurotecnologías, Granada, Spain (June 12-13, 2014). Cognitive Area Networks ISSN: 2341-4243 1, 75-80. [Conference paper]
  • Valderrama J, de la Torre A, Alvarez IM, Segura JC, Kaf W, Sainz M, Vargas JL. A more efficient use of the recording time with randomized stimulation and averaging (RSA) in hearing screening applications. Invited talk (expenses covered) at the 9th International Conference of the Saudi Society of Otorhinolaryngology – Head and Neck Surgery, Riyad, Kingdom of Saudi Arabia (March 4-6, 2014). [Abstract, Presentation]
  • Valderrama J, Morales JM, Alvarez IM, de la Torre A, Segura JC, Sainz M, Vargas JL. Automatic quality assessment and response detection of auditory evoked potentials based on response tracking. Podium presentation at the XXIII International Evoked Response Audiometry Study Group (IERASG) Biennial Symposium, New Orleans, LA (June 9-13, 2013). [Abstract, Presentation]
  • Valderrama J, de la Torre A, Alvarez IM, Segura JC, Thornton ARD, Sainz M, Vargas JL. Auditory middle latency responses recorded at high stimulation rates using randomised stimulation and averaging. Podium presentation at the XXIII International Evoked Response Audiometry Study Group (IERASG) Biennial Symposium, New Orleans, LA (June 9-13, 2013). [Abstract, Presentation]
  • Valderrama J, de la Torre A, Alvarez IM, Segura JC, Sainz M, Vargas JL. Deconvolution of overlapping responses and frequency domain-based artifact rejection methods using randomized stimulation. Podium presentation at the XXIII International Evoked Response Audiometry Study Group (IERASG) Biennial Symposium, New Orleans, LA (June 9-13, 2013). [Abstract, Presentation]
  • Valderrama J, Alvarez IM, de la Torre A, Segura JC, Sainz M, Vargas JL. A portable, modular, and low cost auditory brainstem response recording system including an algorithm for automatic identification of responses suitable for hearing screening. Podium presentation at the IEEE EMBS Point-of-Care Healthcare Technologies (PHT) conference, Bangalore, India (Jan 16-18, 2013), art. 6461314, 180-183. [Conference paper, Presentation]
  • Valderrama J, Alvarez IM, de la Torre A, Segura JC, Sainz M, Vargas JL. A preliminary study of the short-term and long-term neural adaptation of the auditory brainstem response by the use of randomized stimulation. Poster at the Adult Hearing Screening (AHS) congress, Cernobbio (Como Lake), Italy (June 7-9, 2012). [Abstract, Poster]
  • Valderrama J, Alvarez IM, de la Torre A, Segura JC, Sainz M, Vargas JL. Reducing recording time of brainstem auditory evoked responses by the use of randomized stimulation. Poster at the Newborn Hearing Screening (NHS) congress, Cernobbio (Como Lake), Italy (June 5-7, 2012). [Abstract, Poster]
  • Alvarez IM, Valderrama J, de la Torre A, Segura JC, Sainz M, Vargas JL. Reducción del tiempo de exploración de potenciales evocados auditivos del tronco cerebral mediante estimulación aleatorizada. Podium presentation at the XXV Unión Científica Internacional de Radio (URSI) National Symposium, Bilbao, Spain (Sep 15-17, 2010). [Conference paper, Presentation]