Category Archives: UHPLC

Liquid chromatography-tandem mass spectrometry for the determination of multiple mycotoxins in serum through suspect screening and targeted approaches: Advancing human mycotoxin biomonitoring.

Posted on 8 January, 2025 by fqm302

Human biomonitoring (HBM) is accepted as an effective way to assess human exposure to mycotoxins and to investigate their impact on human health. Ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) has emerged as a powerful tool for the quantitative and … Continue reading →

Posted in Human biomonitoring, Human serum, Mass spectrometry, Mycotoxins, PROYEXCEL_00195, Protein precipitation, UHPLC | Tagged , | Comments Off on Liquid chromatography-tandem mass spectrometry for the determination of multiple mycotoxins in serum through suspect screening and targeted approaches: Advancing human mycotoxin biomonitoring.

Emerging mycotoxin occurrence in chicken feed and eggs from Algeria.

Posted on 4 December, 2024 by fqm302

Poultry farming has developed into one of Algeria’s most productive industrial farming because of the growing demand for sources of protein among Algerian society. Laying hen feed consists mainly of cereals, which can be contaminated with molds and subsequently with … Continue reading →

Posted in Animal feed, Eggs, Mass spectrometry, Mycotoxins, QuEChERS, UHPLC | Tagged , , | Comments Off on Emerging mycotoxin occurrence in chicken feed and eggs from Algeria.

Assessing human exposure to pesticides and mycotoxins: optimization and validation of a method for multianalyte determination in urine samples.

Posted on 9 April, 2024 by fqm302

Humans are exposed to an increasing number of contaminants, with diet being one of the most important exposure routes. In this framework, human biomonitoring is considered the gold standard for evaluating human exposure to chemicals. Pesticides and mycotoxins are chemicals … Continue reading →

Posted in Biomonitoring, Mass spectrometry, Mycotoxins, PID2021-127804OB-I00, PROYEXCEL_00195, Pesticides, SALLE, UHPLC, Urine | Tagged , , | Comments Off on Assessing human exposure to pesticides and mycotoxins: optimization and validation of a method for multianalyte determination in urine samples.

Determination of bile acids in serum of pigs exposed to polychlorinated biphenyls by liquid chromatography-mass spectrometry.

Posted on 22 December, 2023 by fqm302

Exposure to polychlorinated biphenyls (PCBs) has been linked to dyslipidemia. Under acute exposure to PCBs, it has been observed that the secretion of bile acids (BAs) can be impacted, limiting (indirectly) lipid absorption in the gut. In this context, two … Continue reading →

Posted in Liquid-liquid extraction, Mass spectrometry, Metabolomics, PID2020–120020RA-I00, Pig serum, Polychlorinated biphenyls, UHPLC | Tagged , , , | Comments Off on Determination of bile acids in serum of pigs exposed to polychlorinated biphenyls by liquid chromatography-mass spectrometry.

Mycotoxin occurrence in milk and durum wheat samples from Tunisia using dispersive liquid–liquid microextraction and liquid chromatography with fluorescence detection.

Posted on 30 October, 2023 by fqm302

Food and feed contamination with mycotoxins is a major public health concern. Humans and animals are exposed to these toxins by consuming contaminated products throughout their lives. In this study, a method based on dispersive liquid–liquid microextraction (DLLME), followed by … Continue reading →

Posted in Aflatoxins, DLLME, Durum wheat, Fluorescence, Milk, Mycotoxins, PID2021-127804OB-I00, PROYEXCEL_00195, Photo-induced, UHPLC | Tagged , , | Comments Off on Mycotoxin occurrence in milk and durum wheat samples from Tunisia using dispersive liquid–liquid microextraction and liquid chromatography with fluorescence detection.

Ion mobility-mass spectrometry to extend analytical performance in the determination of ergot alkaloids in cereal samples.

Posted on 26 September, 2022 by fqm302

This work evaluates the potential of ion mobility spectrometry (IMS) to improve the analytical performance of current liquid chromatography-mass spectrometry (LC-MS) workflows applied to the determination of ergot alkaloids (EAs) in cereal samples. Collision cross section (CCS) values for EA … Continue reading →

Posted in Barley, Ergot alkaloids, Ion mobility, PID2021-127804OB-I00, QuEChERS, UHPLC, Wheat | Tagged , , | Comments Off on Ion mobility-mass spectrometry to extend analytical performance in the determination of ergot alkaloids in cereal samples.

Determination of principal ergot alkaloids in swine feeding

Posted on 2 September, 2021 by fqm302

Ergot alkaloids are secondary metabolites produced by fungi in the genus Claviceps. They contaminate a large variety of cereals, such as rye, triticale, wheat and barley. The ingestion of contaminated cereals might cause adverse health effects in humans and animals. … Continue reading →

Posted in Animal feed, Ergot alkaloids, Mass spectrometry, QuEChERS, RTI2018-097043-B-I00, UHPLC | Tagged , , | Comments Off on Determination of principal ergot alkaloids in swine feeding

Determination of the main ergot alkaloids and their epimers in oat-based functional foods by ultra-high performance liquid chromatography tandem mass spectrometry.

Posted on 18 June, 2021 by fqm302

An ultra-high performance liquid chromatography coupled to tandem mass spectrometry method is proposed for the determination of the major ergot alkaloids (ergometrine, ergosine, ergotamine, ergocornine, ergokryptine, ergocristine) and their epimers (ergometrinine, ergosinine, ergotaminine, ergocorninine, ergokryptinine, and ergocristinine) in oat-based foods … Continue reading →

Posted in Ergot alkaloids, Mass spectrometry, Mycotoxins, Oat, QuEChERS, RTI2018-097043-B-I00, UHPLC | Tagged , , | Comments Off on Determination of the main ergot alkaloids and their epimers in oat-based functional foods by ultra-high performance liquid chromatography tandem mass spectrometry.

Occurrence of ergot alkaloids in barley and wheat from Algeria

Posted on 28 April, 2021 by fqm302

The natural occurrence of six major ergot alkaloids, ergometrine, ergosine, ergotamine, ergocornine, ergokryptine and ergocristine, as well as their corresponding epimers, were investigated in 60 cereal samples (barley and wheat) from Algeria. Ultra-high performance liquid chromatography coupled to tandem mass … Continue reading →

Posted in Barley, Ergot alkaloids, Mass spectrometry, Mycotoxins, QuEChERS, RTI2018-097043-B-I00, UHPLC, Wheat | Tagged , , | Comments Off on Occurrence of ergot alkaloids in barley and wheat from Algeria

Determination of sulfonylurea pesticide residues in edible seeds used as nutraceuticals by QuEChERS in combination with ultra-high-performance liquid chromatography-tandem mass spectrometry

Posted on 13 April, 2020 by fqm302

This work proposes a novel Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS) method in combination with ultra-high performance liquid chromatography-tandem mass spectrometry for the determination of sulfonylurea residues in edible seeds. The chromatographic separation of nine sulfonylureas was accomplished … Continue reading →

Posted in AGL2015-70708-R, Mass spectrometry, QuEChERS, Seeds, Sulfonylurea, UHPLC | Tagged , , | Comments Off on Determination of sulfonylurea pesticide residues in edible seeds used as nutraceuticals by QuEChERS in combination with ultra-high-performance liquid chromatography-tandem mass spectrometry