Category Archives: Chromatography

Assessing human exposure to pesticides and mycotoxins: optimization and validation of a method for multianalyte determination in urine samples.

Posted on 9 April, 2024 by fqm302

Humans are exposed to an increasing number of contaminants, with diet being one of the most important exposure routes. In this framework, human biomonitoring is considered the gold standard for evaluating human exposure to chemicals. Pesticides and mycotoxins are chemicals … Continue reading →

Posted in Biomonitoring, Mass spectrometry, Mycotoxins, PID2021-127804OB-I00, PROYEXCEL_00195, Pesticides, SALLE, UHPLC, Urine | Tagged , , | Comments Off on Assessing human exposure to pesticides and mycotoxins: optimization and validation of a method for multianalyte determination in urine samples.

Determination of bile acids in serum of pigs exposed to polychlorinated biphenyls by liquid chromatography-mass spectrometry.

Posted on 22 December, 2023 by fqm302

Exposure to polychlorinated biphenyls (PCBs) has been linked to dyslipidemia. Under acute exposure to PCBs, it has been observed that the secretion of bile acids (BAs) can be impacted, limiting (indirectly) lipid absorption in the gut. In this context, two … Continue reading →

Posted in Liquid-liquid extraction, Mass spectrometry, Metabolomics, PID2020–120020RA-I00, Pig serum, Polychlorinated biphenyls, UHPLC | Tagged , , , | Comments Off on Determination of bile acids in serum of pigs exposed to polychlorinated biphenyls by liquid chromatography-mass spectrometry.

Mycotoxin occurrence in milk and durum wheat samples from Tunisia using dispersive liquid–liquid microextraction and liquid chromatography with fluorescence detection.

Posted on 30 October, 2023 by fqm302

Food and feed contamination with mycotoxins is a major public health concern. Humans and animals are exposed to these toxins by consuming contaminated products throughout their lives. In this study, a method based on dispersive liquid–liquid microextraction (DLLME), followed by … Continue reading →

Posted in Aflatoxins, DLLME, Durum wheat, Fluorescence, Milk, Mycotoxins, PID2021-127804OB-I00, PROYEXCEL_00195, Photo-induced, UHPLC | Tagged , , | Comments Off on Mycotoxin occurrence in milk and durum wheat samples from Tunisia using dispersive liquid–liquid microextraction and liquid chromatography with fluorescence detection.

Deeper insights into the effects of low dietary levels of polychlorinated biphenyls on pig metabolism using gas chromatography-high resolution mass spectrometry metabolomics.

Posted on 6 September, 2023 by fqm302

Polychlorinated biphenyls (PCBs) are a class of contaminants of great concern, linked to the development of many chronic diseases. Adverse effects of PCBs have been documented in humans after accidental and massive exposure. However, little is known about the effect … Continue reading →

Posted in Contaminants, GC, Mass spectrometry, Metabolomics, PID2020–120020RA-I00, Pig serum, Polychlorinated biphenyls | Tagged , , | Comments Off on Deeper insights into the effects of low dietary levels of polychlorinated biphenyls on pig metabolism using gas chromatography-high resolution mass spectrometry metabolomics.

A comparison of hydrophilic interaction liquid chromatography and capillary electrophoresis for the metabolomics analysis of human serum.

Posted on 6 August, 2023 by fqm302

Cationic, anionic, zwitterionic and, partially polar metabolites are very important constituents of blood serum. Several of these metabolites underpin the core metabolism of cells (e.g., Krebs cycle, urea cycle, proteins synthesis, etc.), while others might be considered ancillary but still … Continue reading →

Posted in CZE, HILIC, Human serum, Metabolomics, PID2020–120020RA-I00, PROYEXCEL_00195 | Tagged , , | Comments Off on A comparison of hydrophilic interaction liquid chromatography and capillary electrophoresis for the metabolomics analysis of human serum.

Analytical methods based on liquid chromatography and capillary electrophoresis to determine neonicotinoid residues in complex matrices. A comprehensive review.

Posted on 30 July, 2023 by fqm302

Neonicotinoids (NNIs) are neuro-active and systemic insecticides widely used to protect crops from pest attack. During the last decades, there has been an increase concern about their uses and toxic effects, especially to beneficial and non-target insects such as pollinators. … Continue reading →

Posted in B-AGR-202-UGR20, Chromatography, Electrophoresis, Neonicotinoids, Review | Tagged | Comments Off on Analytical methods based on liquid chromatography and capillary electrophoresis to determine neonicotinoid residues in complex matrices. A comprehensive review.

Determination of multiclass cyanotoxins in blue-green algae (BGA) dietary supplements using hydrophilic interaction liquid chromatography-tandem mass spectrometry.

Posted on 7 February, 2023 by fqm302

In recent years, the consumption of blue-green algae (BGA) dietary supplements is increasing because of their health benefits. However, cyanobacteria can produce cyanotoxins, which present serious health risks. In this work we propose hydrophilic interaction liquid chromatography coupled with tandem … Continue reading →

Posted in B-AGR-202-UGR20, Blue-green algae, Cyanotoxins, HILIC, Mass spectrometry, RTI2018-097043-B-I00, SPE | Tagged , , | Comments Off on Determination of multiclass cyanotoxins in blue-green algae (BGA) dietary supplements using hydrophilic interaction liquid chromatography-tandem mass spectrometry.

Ion mobility-mass spectrometry to extend analytical performance in the determination of ergot alkaloids in cereal samples.

Posted on 26 September, 2022 by fqm302

This work evaluates the potential of ion mobility spectrometry (IMS) to improve the analytical performance of current liquid chromatography-mass spectrometry (LC-MS) workflows applied to the determination of ergot alkaloids (EAs) in cereal samples. Collision cross section (CCS) values for EA … Continue reading →

Posted in Barley, Ergot alkaloids, Ion mobility, PID2021-127804OB-I00, QuEChERS, UHPLC, Wheat | Tagged , , | Comments Off on Ion mobility-mass spectrometry to extend analytical performance in the determination of ergot alkaloids in cereal samples.

Multiclass cyanotoxin analysis in reservoir waters: Tandem solid-phase extraction followed by zwitterionic hydrophilic interaction liquid chromatography-mass spectrometry.

Posted on 29 November, 2021 by fqm302

The presence of cyanobacteria and cyanotoxins in all water bodies, including ocean water and fresh water sources, represents a risk for human health as eutrophication and climate change are enhancing their level of proliferation. For risk assessment and studies on … Continue reading →

Posted in Cyanotoxins, HILIC, Mass spectrometry, RTI2018-097043-B-I00, SPE, Water | Tagged , , | Comments Off on Multiclass cyanotoxin analysis in reservoir waters: Tandem solid-phase extraction followed by zwitterionic hydrophilic interaction liquid chromatography-mass spectrometry.

A natural deep eutectic solvent as a novel dispersive solvent in dispersive liquid-liquid microextraction based on solidification of floating organic droplet for the determination of pesticide residues.

Posted on 17 November, 2021 by fqm302

Current trends in analytical chemistry encourage the use of innocuous solvents to develop modern methods aligned with green chemistry. In this sense, natural deep eutectic solvents (NADESs) have emerged as a novel generation of green solvents which can be employed … Continue reading →

Posted in Fipronil, HPLC, NADES, RED2018-102522-T, UV-vis, Water, Wine | Tagged , | Comments Off on A natural deep eutectic solvent as a novel dispersive solvent in dispersive liquid-liquid microextraction based on solidification of floating organic droplet for the determination of pesticide residues.