Category Archives: Drugs

Collision cross section (CCS) database: an additional measure to characterize steroids.

Posted on 10 May, 2018 by fqm302

Ion mobility spectrometry enhances the performance characteristics of liquid chromatography–mass spectrometry workflows intended to steroid profiling by providing a new separation dimension and a novel characterization parameter, the so-called collision cross section (CCS). This work proposes the first CCS database … Continue reading →

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On-line preconcentration strategy for the simultaneous quantification of three local anaesthetics in human urine using capillary zone electrophoresis

Posted on 15 December, 2015 by fqm302

The simultaneous determination of usually employed anaesthetics (procaine, lidocaine and bupivacaine) has been developed and validated using capillary electrophoresis with ultraviolet detection at 212 nm. The separation of these three drugs has been achieved in less than 7 min, using … Continue reading →

Posted in Anaesthetics, CZE, FASI, UV-vis, Urine | Comments Off on On-line preconcentration strategy for the simultaneous quantification of three local anaesthetics in human urine using capillary zone electrophoresis

Mass spectrometric and contactless conductivity detection approaches in the determination of muscle relaxants by capillary electrophoresis

Posted on 12 September, 2013 by fqm302

Novel and rapid capillary electrophoresis-coupled tandem mass spectrometry (CE-MS/MS) and capillary electrophoresis with capacitively coupled contactless conductivity detection (CE-C4D) methods have been developed for the separation and determination of three neuromuscular blocking agents: pancuronium, vecuronium, and rocuronium. In both cases, … Continue reading →

Posted in C4D, CZE, Cyclodextrins, Mass spectrometry, Muscle relaxants, Pharmaceutical formulations | Tagged , | Comments Off on Mass spectrometric and contactless conductivity detection approaches in the determination of muscle relaxants by capillary electrophoresis

Dispersive liquid-liquid microextraction prior to field-amplified sample injection for the sensitive analysis of 3,4- methylenedioxymetamphetamine, phencyclidine and lysergic acid diethylamide by capillary electrophoresis in human urine

Posted on 13 November, 2012 by fqm302

A novel capillary zone electrophoresis (CZE) with ultraviolet detection method has been developed and validated for the analysis of 3,4-methylenedioxymethamphetamine (MDMA), lysergic acid diethylamide (LSD) and phencyclidine (PCP) in human urine. The separation of these three analytes has been achieved … Continue reading →

Posted in Biological fluids, CZE, DLLME, Drugs, Electrophoresis, FASI, UV-vis, Urine | Tagged | Comments Off on Dispersive liquid-liquid microextraction prior to field-amplified sample injection for the sensitive analysis of 3,4- methylenedioxymetamphetamine, phencyclidine and lysergic acid diethylamide by capillary electrophoresis in human urine

Advances in the determination of β-lactam antibiotics by liquid chromatography

Posted on 15 August, 2012 by fqm302

β-lactam antibiotics have been the most widely used antimicrobial drugs for more than 80 years and still constitute the most important group of antibiotics. Their extensive use in veterinary medicine practices as growth promoters, and chemotherapeutic and/or prophylactic agents causes numerous … Continue reading →

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Capillary electrophoresis for the analysis of drugs of abuse in biological specimens of forensic interest

Posted on 21 December, 2011 by fqm302

We review analytical methodologies using capillary electrophoresis and related  techniques (micellar electrokinetic chromatography and capillary electrochromatography) with detection systems (ultraviolet-visible spectrometry, fluorescence, laser-induced fluorescence and mass spectrometry) for quantification of drugs of abuse and their metabolites in biological specimens of … Continue reading →

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Desarrollo de un método MEKC para la determinación de 5-nitroimidazoles en aguas de río

Posted on 20 September, 2011 by fqm302

Los 5-nitroimidazoles (5-NDZs) son antimicrobianos con propiedades antibacterianas y antiprotozoarias. Debido a estas características se ha extendido su uso tanto como antibióticos humanos como veterinarios, mostrando eficacia contra la mayoría de bacterias anaerobias Gram negativas y algunas Gram positivas (Bacteroides … Continue reading →

Posted in 5-nitroimidazoles, Drugs, MEKC, SPE, Trabajo fin máster, UV-vis, Water | Comments Off on Desarrollo de un método MEKC para la determinación de 5-nitroimidazoles en aguas de río

Peroxyoxalate photoinduced chemiluminescence detection of norfloxacin in pharmaceutical products by flow injection analysis

Posted on 28 January, 2010 by fqm302

A new method for the determination of norfloxacin by flow injection analysis based on photoinduced chemiluminescence detection is proposed. We have selected the peroxyoxalate (PO) reaction based on the possibility of detecting fluorescent products derived from a photochemically induced decomposition … Continue reading →

Posted in Antibiotics, Chemiluminescence, Drugs, Flow injection analysis, Photoinduced, Quinolones | Tagged , | Comments Off on Peroxyoxalate photoinduced chemiluminescence detection of norfloxacin in pharmaceutical products by flow injection analysis