Applications of capillary electrophoresis with chemiluminescence detection in clinical, environmental and food analysis. A review.

  • Acknowledgements: Financial support of the “Junta de Andalucía” (Project P12-AGR-1647). JFHP and DAR thanks the Ministry of Economy and Competitiveness of the Spanish Government for Juan de la Cierva postdoctoral contracts (JCI-2011-10603 and JCI-2010-07345). FJL is grateful for personal funding through the Andalucía Talent Hub Program co-funded by the European Union's Seventh Framework Program, Marie Skłodowska-Curie actions (COFUND – Grant Agreement no. 291780) and the Ministry of Economy, Innovation, Science and Employment of the Junta de Andalucía.
  • Authors: Francisco J. Lara, Diego Airado-Rodríguez, David Moreno-González, José F. Huertas-Pérez, Ana M. García-Campaña
  • Reference: Analytica Chimica Acta 913 (2016) 22-40.

This paper reviews the latest developments and analytical applications of chemiluminescence detection coupled to capillary electrophoresis (CE-CL). Different sections considering the most common CL systems have been included, such as the tris(2,2ʹ-bipyridine)ruthenium(II) system, the luminol and acridinium derivative reactions, the peroxyoxalate CL or direct oxidations. Improvements in instrumental designs, new strategies for improving both resolution and sensitivity, and applications in different fields such as clinical, pharmaceutical, environmental and food analysis have been included. This review covers the literature from 2010 to 2015.

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