- Acknowledgements: The authors gratefully acknowledge the financial support of the Junta de Andalucía (Excellence Project Ref: P12-AGR-1647). A.M.H. thanks the “Erasmus Mundus – Al Idrisi II program” for a doctoral grant (2013 – 2401 / 001 – 001 – EMA2). D.M.G. acknowledges MINECO for a Juan de la Cierva postdoctoral research contract (ref. JCI-2014-19573).
- Authors: A.M. Hamed, D. Moreno-González, L. Gámiz-Gracia, A.M. García-Campaña.
- Reference: Journal Separation Science 40 (2017) 488-496.
A simple and efficient method for the determination of 28 carbamates in high-fat cheeses is proposed. The methodology is based on a modified quick, easy, cheap, effective, rugged, and safe procedure as sample treatment using a new sorbent (Z-Sep+) followed by ultra-high performance liquid chromatography with tandem mass spectrometry determination. The method has been validated in different kinds of cheese (Gorgonzola, Roquefort, and Camembert), achieving recoveries of 70–115%, relative standard deviations lower than 13% and limits of quantification lower than 5.4 μg/kg, below the maximum residue levels tolerated for these compounds by the European legislation. The matrix effect was lower than ±30% for all the studied pesticides. The combination of ultra-high performance liquid chromatography and tandem mass spectrometry with this modified quick, easy, cheap, effective, rugged, and safe procedure using Z-Sep+ allowed a high sample throughput and an efficient cleaning of extracts for the control of these residues in cheeses with a high fat content.
